Thiamet G

CAS No. 1009816-48-1

Thiamet G ( Thiamet G; Thiamet-G )

Catalog No. M17115 CAS No. 1009816-48-1

Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37, 000-fold selectivity over human lysosomal –hexosaminidase.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 33 Get Quote
5MG 51 Get Quote
10MG 85 Get Quote
25MG 178 Get Quote
50MG 325 Get Quote
100MG 483 Get Quote
500MG 1071 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Thiamet G
  • Note
    Research use only, not for human use.
  • Brief Description
    Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37, 000-fold selectivity over human lysosomal –hexosaminidase.
  • Description
    Thiamet G is a potent and selective inhibitor of O-GlcNAcase.
  • Synonyms
    Thiamet G; Thiamet-G
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    O-GlcNAcase
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1009816-48-1
  • Formula Weight
    248.3
  • Molecular Formula
    C9H16N2O4S
  • Purity
    98%
  • Solubility
    H2O : ≥ 50 mg/mL 201.37 mM DMSO : ≥ 45 mg/mL181.23 mM
  • SMILES
    [H][C@]12O[C@H](CO)[C@@H](O)[C@H](O)[C@@]1([H])N=C(NCC)S2
  • Chemical Name
    (3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-5H-pyrano[3,2-d]thiazole-6,7-diol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yuzwa SA, et al. Nat Chem Biol. 2008, 4(8), 483-490.
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